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Proto-Oncogene Proteins pp60(c-src)

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Definition: Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to PP60(V-SRC) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.      Other names src Proto-Oncogene Protein pp60; pp60(c-src); c-src Protein pp60; src Proto Oncogene Protein pp60; src Proto Oncogene Product; pp60, c-src Protein; pp60 c src; c-src, pp60; c src Protein pp60; Proto-Oncogene Product, src; Proto Oncogene Protein src; Protein src, Proto-Oncogene; Protein pp60, c-src; src Proto-Oncogene Product; pp60 c-src; Proto-Oncogene Protein src; Proto-Oncogene Protein pp60(c-src); Phosphoprotein pp60(c-src)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Sla protein, rat  0   *Proto-Oncogene Proteins pp60(c-src) *Adaptor Proteins, Signal Transducing src Homology Domains.
SLA protein, human  0   *Proto-Oncogene Proteins pp60(c-src) *Adaptor Proteins, Signal Transducing src Homology Domains.
Sla2 protein, mouse  0   *Proto-Oncogene Proteins pp60(c-src) *Adaptor Proteins, Signal Transducing src Homology Domains.
4-(2-acetamido-3-(1-(3-carbamoyl-4-(cyclohexylmethoxy)phenyl)ethylamino)-3-oxopropyl)-2-(carboxymethoxy)benzenephosphonic acid  0   *Benzamides *Phosphonic Acids Proto-Oncogene Proteins pp60(c-src)/antagonists & inhibitors. Bioorg Med Chem Lett 2001 Sep 3;11(17):2319-23
SLA2 protein, human  0   *Proto-Oncogene Proteins pp60(c-src) *Adaptor Proteins, Signal Transducing src Homology Domains. J Exp Med 2001 Nov 5;194(9):1263-76
proto-oncogene protein pp60(c-Src) (140-157)  0   *Peptide Fragments *Proto-Oncogene Proteins pp60(c-src) Protein-Tyrosine Kinases/antagonists & inhibitors. Dev Biol 1999 May 15;209(2):308-20
acetyl-phosphotyrosyl-N,N-dipentylglutamamide  0   *Dipeptides Proto-Oncogene Proteins pp60(c-src)/antagonists & inhibitors. J Med Chem 1998 May 21;41(11):1894-908
Src42A protein, Drosophila  EC 2.7.1.112   *Proto-Oncogene Proteins pp60(c-src) *Drosophila Proteins. Genes Dev 1996 Jul 1;10(13):1645-56
Sla protein, mouse  0   *Proto-Oncogene Proteins pp60(c-src) src Homology Domains. J Biol Chem 1995 Aug 18;270(33):19201-4
Matk protein, mouse  EC 2.7.1.-   *Proto-Oncogene Proteins pp60(c-src). Proc Natl Acad Sci U S A 1994 Mar 29;91(7):2597-601
MATK protein, human  EC 2.7.1.112   *Proto-Oncogene Proteins pp60(c-src) Megakaryocytes. J Biol Chem 1994 Jan 14;269(2):1068-74

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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