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Ribonucleoproteins, Small Nuclear

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Definition: Highly conserved nuclear RNA-protein complexes that function in RNA processing in the nucleus, including pre-mRNA splicing and pre-mRNA 3'-end processing in the nucleoplasm, and pre-rRNA processing in the nucleolus (see RIBONUCLEOPROTEINS, SMALL NUCLEOLAR).     
Examples Ribonucleoproteins, Small Nucleolar; Ribonucleoprotein, U1 Small Nuclear; Ribonucleoprotein, U2 Small Nuclear; Ribonucleoprotein, U4-U6 Small Nuclear; Ribonucleoprotein, U5 Small Nuclear; Ribonucleoprotein, U7 Small Nuclear; snRNP Core Proteins
Other names snRNP; Small Nuclear Ribonucleoproteins; Ribonucleoprotein, Small Nuclear; RNP, Small Nuclear; Nuclear Ribonucleoproteins, Small; Nuclear Ribonucleoprotein, Small; Nuclear RNP, Small; Small Nuclear Ribonucleoprotein Particle; Small Nuclear Ribonucleoprotein; Small Nuclear RNP
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NOP10 protein, zebrafish  0   *Ribonucleoproteins, Small Nuclear *Zebrafish Proteins. Blood. 2011 Nov 17;118(20):5458-65.
ZCRB1 protein, human  0   *Ribonucleoproteins, Small Nuclear.
SNRNP25 protein, human  0   *Ribonucleoproteins, Small Nuclear.
SNRNP35 protein, human  0   *Ribonucleoproteins, Small Nuclear.
U11/U12 small nuclear ribonucleoprotein  0   *Ribonucleoproteins, Small Nuclear.
SNRNP48 protein, human  0   *Ribonucleoproteins, Small Nuclear.
EDC3 protein, mouse  0   *Ribonucleoproteins, Small Nuclear. Mol Cell Proteomics 2010 Apr;9(4):682-94
SNRNP200 protein, human  0   *Ribonucleoproteins, Small Nuclear. Am J Hum Genet 2009 Nov;85(5):617-27
Lsm11 protein, Drosophila  0   *Ribonucleoproteins, Small Nuclear *Drosophila Proteins. RNA 2009 Sep;15(9):1661-72
Lsm10 protein, Drosophila  0   *Ribonucleoproteins, Small Nuclear *Drosophila Proteins. RNA 2009 Sep;15(9):1661-72
EDC3 protein, human  0   *Ribonucleoproteins, Small Nuclear. Mol Cell Biol 2007 Dec;27(24):8600-11
Edc3 protein, Drosophila  0   *Ribonucleoproteins, Small Nuclear *Drosophila Proteins. Mol Cell Biol 2007 Dec;27(24):8600-11
Utp20 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. RNA 2007 Sep;13(9):1516-27
Utp10 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. RNA 2007 Sep;13(9):1516-27
U1L protein, S pombe  0   *Ribonucleoproteins, Small Nuclear *Schizosaccharomyces pombe Proteins. Nucleic Acids Res 2007;35(5):1391-401
U1J protein, S pombe  0   *Ribonucleoproteins, Small Nuclear *Schizosaccharomyces pombe Proteins. Nucleic Acids Res 2007;35(5):1391-401
U1H protein, S pombe  0   *Ribonucleoproteins, Small Nuclear *Schizosaccharomyces pombe Proteins. Nucleic Acids Res 2007;35(5):1391-401
HEXIM2 protein, human  0   *Ribonucleoproteins, Small Nuclear. J Biol Chem 2005 Apr 22;280(16):16360-7
Sart1 protein, rat  0   *Antigens, Neoplasm *Ribonucleoproteins, Small Nuclear DNA-Binding Proteins Leucine Zippers.
Lsm8 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2004 Nov;24(21):9646-57
Lsm2 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2004 Nov;24(21):9646-57
RNP-C protein, Xenopus  0   *Ribonucleoproteins, Small Nuclear *Xenopus Proteins.
SNRPC protein, human  0   *Ribonucleoproteins, Small Nuclear.
SLU7 protein, human  0   *Ribonucleoproteins, Small Nuclear.
SmD3 protein, Drosophila  0   *Ribonucleoproteins, Small Nuclear *Drosophila Proteins RNA Splicing.
Snrpd1 protein, mouse  0   *Ribonucleoproteins, Small Nuclear.
SMB protein, S cerevisiae  0   *Autoantigens *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins.
Tdrd1 protein, mouse  0   *Ribonucleoproteins, Small Nuclear. Mech Dev 2003 Sep;120(9):979-90
U11 small nuclear ribonucleoprotein, Drosophila  0   *Ribonucleoproteins, Small Nuclear *Drosophila Proteins. Proc Natl Acad Sci U S A 2004 Jun 29;101(26):9584-9
LSm4 protein, Xenopus  0   *Ribonucleoproteins, Small Nuclear *Xenopus Proteins.
LSM4 protein, human  0   *Ribonucleoproteins, Small Nuclear.
(U4-U6.U5)tri-snRNP-specific protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins.
Lsm11 protein, mouse  0   *Ribonucleoproteins, Small Nuclear. Genes Dev 2003 Sep 15;17(18);2321-33
GEMIN6 protein, human  0   *Ribonucleoproteins, Small Nuclear. J Biol Chem 2002 Mar 1;277(9):7540-5
GEMIN5 protein, human  0   *Ribonucleoproteins, Small Nuclear. J Biol Chem 2002 Feb 15;277(7):5631-6
Snu66 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. RNA 2001 Nov;7(11):1543-53
Snu23 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. RNA 2001 Nov;7(11):1543-53
Snu13 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. RNA 2001 Nov;7(11):1543-53
LSM10 protein, human  0   *Ribonucleoproteins, Small Nuclear Protein Subunits. Development 2001 Oct;128(19):3795-8075470-9
SART1 protein, human  0   *Antigens, Neoplasm *Ribonucleoproteins, Small Nuclear DNA-Binding Proteins Leucine Zippers. EMBO J 2001 May 15;20(10):2553-63; J Exp Med 1998 Feb 2;187(3):277-88
Sm2 protein, Archaeoglobus fulgidus  0   *Ribonucleoproteins, Small Nuclear *Archaeal Proteins. EMBO J 2001 May 1;20(9):2293-303
Sm1 protein, Archaeoglobus fulgidus  0   *Ribonucleoproteins, Small Nuclear *Archaeal Proteins. EMBO J 2001 May 1;20(9):2293-303
PRP6 protein, Entamoeba histolytica  0   *Ribonucleoproteins, Small Nuclear. Arc Med Res 2000 Jul-Aug;31(4 Suppl):S294-5
NHP2 protein, human  0   *Nuclear Proteins *Ribonucleoproteins, Small Nuclear RNA, Small Nuclear. Mol Cell Biol 2000 Dec;20(23):9028-40
GEMIN4 protein, human  0   *Ribonucleoproteins, Small Nuclear. J Cell Biol 2000 Mar 20;148(6):1177-86
Lsm4 protein, mouse  0   *Ribonucleoproteins, Small Nuclear. Mol Cel Biol 2000 Feb;20(3):1055-62
NHP2L1 protein, human  0   *Ribonucleoproteins, Small Nuclear. EMBO J 1999 Nov 1;18(21):6119-33
Prp24 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. Genes Dev 1991 May;5(5):773-85
SmE protein, Leptomonas collosoma  0   *Protozoan Proteins *Ribonucleoproteins, Small Nuclear. J Biol Chem 1999 Apr 30;274(18):12217-21
Spp381 protein, S cerevisiae  0   *Nuclear Proteins *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1999 Jan;19(1):577-84
Pad-1 protein, Neurospora crassa  0   *Fungal Proteins *Ribonucleoproteins, Small Nuclear RNA Splicing. Fungal Genet Biol 1998 Mar;23(2):169-80
SME1 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1998 Apr;18(4):1956-66
Lsm2 protein, mouse  0   *Ribonucleoproteins, Small Nuclear. Immunogenetics 1997;46(5):427-30
LSM2 protein, human  0   *Ribonucleoproteins, Small Nuclear. Genetica 1996 Jan;97(1):117-25
tri-snRNP-specific protein, 27-kDa, human  0   *Ribonucleoproteins, Small Nuclear. RNA 1997 Apr;3(4):344-55
Snrp1c protein, mouse  0   *Ribonucleoproteins, Small Nuclear. Gene 1997 Jan 15;184(2):273-8
BRR1 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. EMBO J 1996 Aug 15;15(16):4368-79
U11 small nuclear ribonucleoprotein, human  0   *Ribonucleoproteins, Small Nuclear. Cell 1996 Mar 8;84(5):801-11
SLU7 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. EMBO J 1995 Aug 15;14(16):4001-9
SMD3 protein, S cerevisiae  0   *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1995 Jan;15(1):445-55
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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