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Glutamic Acid

More information in Books or onNLM PubMed
Definition: A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.  /agon   
See Also Receptors, Glutamate
Examples 1-Carboxyglutamic Acid; Glutamates; Pyrrolidonecarboxylic Acid 		Other names L Glutamic Acid; L Glutamate; D Glutamate; L-Glutamic Acid; L-Glutamate; Glutamic Acid, (D)-Isomer; D-Glutamate; Glutamate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ethylenediamine-N,N'-diglutaric acid  0   Glutamic Acid/*analogs & derivatives. J Environ Sci Health A Tox Hazard Subst Environ Eng 2011;46(6):533-9
glutamic acid-beta-cyclodextrin  0   *Glutamic Acid *beta-Cyclodextrins. J Environ Sci (China). 2010;22(12):1910-5
2-(3-((4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenylamino)methyl)benzamido)pentanedioic acid  0   *Thiazolidinediones Glutamic Acid/*analogs & derivatives. J Med Chem 2010 Sep 23;53(18):6584-94
N-(4-((2,4-diamino-5-methyl-furo(2,3-d)pyrimidin-6-yl)thio)-benzoyl)-L-glutamic acid  0   *Pyrimidines Glutamic Acid/*analogs & derivatives. Bioorg Med Chem. 2010 Jan 15;18(2):953-61
glutamate anhydride  0   *Anhydrides Glutamic Acid/*analogs & derivatives. Proteins 2008 May 1;71(2):1038-41
N-dodecylglutamic acid  0   Glutamic Acid/*analogs & derivatives. J Colloid Interface Sci 2007 Jul 1;311(1):276-84
N',N''-dibutyl-N-(4-carboxybutanoyl)glutamide  0   Glutamic Acid/*analogs & derivatives. J Chromatogr A 2006 Jun 30;1119(1-2):105-14
N',N''-dioctadecyl-N-(4-carboxybutanoyl)glutamide  0   Glutamic Acid/*analogs & derivatives. J Chromatogr A 2006 Jun 30;1119(1-2):105-14
LY329201  0   Glutamic Acid/*analogs & derivatives. Clin Exp Rheumatol 2005 Jul-Aug;23(4):438-46
N-(4-(4-(2,4-diaminofuro(2,3-d)pyrimidin-5-yl)butyl)benzoyl)glutamic acid  0   *Pyrimidines Glutamic Acid/*analogs & derivatives. J Med Chem 2005 Aug 11;48(16):5329-36
N-(4-(4-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimidin-6-yl)butyl)benzoyl)glutamic acid  0   *Pyrimidinones Glutamic Acid/*analogs & derivatives. J Med Chem 2005 Aug 11;48(16):5329-36
N-(4-(5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl)benzoyl)-L-glutamic acid  0   *Pyrimidines Glutamic Acid/*analogs & derivatives. Bioorg Med Chem. 2005 May 16;13(10):3593-9
trujillon  0   *Boron Compounds Glutamic Acid/*analogs & derivatives. Chirality. 2004 Nov;16(9):586-91
gamma-glutamylacyclovir  0   Acyclovir/*analogs & derivatives Glutamic Acid/*analogs & derivatives. Curr Eye Res 2004 Aug-Sep;29(2-3):153-66
(3,5-difluoro-4-(bis(2-chloroethyl)amino)phenyl)carbamoyl-glutamic acid  0   *Nitrogen Mustard Compounds Glutamic Acid/*analogs & derivatives. J Med Chem 2004 May 6;47(10):2651-8
N-(1-deoxyfructos-1-yl)glutamic acid  0   Fructose/*analogs & derivatives Glutamic Acid/*analogs & derivatives. J Agric Food Chem 2003 Aug 27;51(18):5428-36
N-(glucos-1-yl)glutamic acid  0   *Glucosides Glutamic Acid/*analogs & derivatives. J Agric Food Chem 2003 Aug 27;51(18):5428-36
monomethoxypolyethylene glycol-glutamic acid  0   *Polyethylene Glycols Glutamic Acid/*analogs & derivatives. Biotechnol Lett 2003 Feb;25(4):327-30
N-(4-((2,4-diaminoquinazoline-6-yl)methylene)oxycarbonyl)benzoyl glutamic acid  0   *Quinazolines Glutamic Acid/*analogs & derivatives Tetrahydrofolate Dehydrogenase/antagonists & inhibitors. J Med Chem 2003 Jul 31;46(16):3455-62
N-(6-Amino-3,4-dihydro-3-methyl-5-nitroso-4-oxopyrimidin-2-yl)-glutamic acid  0   *Pyrimidines Glutamic Acid/*analogs & derivatives. Acta Crystallogr C. 2003 Apr;59(Pt 4):O210-12
4-(N-(4'-bis(2''-iodoethyl)aminophenyl)-N-methylcarbamoyloxymethyl)phenylcarbamoylglutamic acid  0   *Carbamates Glutamic Acid/*analogs & derivatives. J Med Chem 2003 Apr 24;46(9):1690-705
N-(2-amino-4-ethyl-6-methyl((pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)glutamic acid  0   *Pyrimidines Glutamic Acid/*analogs & derivatives Tetrahydrofolate Dehydrogenase/antagonists & inhibitors Thymidylate Synthase/antagonists & inhibitors. J Med Chem 2003 Feb 13;46(4):591-600
N-(2-amino-4-ethyl((pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)glutamic acid  0   *Pyrimidines Glutamic Acid/*analogs & derivatives Tetrahydrofolate Dehydrogenase/antagonists & inhibitors Thymidylate Synthase/antagonists & inhibitors. J Med Chem 2003 Feb 13;46(4):591-600
N-(4-(1-ethyl-2-(2,4-diaminofuro(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-glutamic acid  0   *Pyrimidines Glutamic Acid/*analogs & derivatives. J Med Chem 2002 Apr 25;45(9):1942-8
tetramethylrhodaminethiocarbamoyl-(Glu(1))  0   *Rhodamines Glutamic Acid/*analogs & derivatives. Regul Pept 2001 Dec 15;102(2-3):111-7
3-methylglutamic acid  0   Glutamic Acid/*analogs & derivatives. J Neurochem 2001 Apr;77(2):550-7
thioglutamic acid  0   Glutamic Acid/*analogs & derivatives. Orig Life Evol Biosph 2000 Oct;30(5):423-30
N-(2-amino-4-methyl((pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)glutamic acid  0   *Pyrimidines Glutamic Acid/*analogs & derivatives Thymidylate Synthase/antagonists & inhibitors. J Med Chem 2000 Oct 19;43(21):3837-51
4-hydroxy-4-(indol-3-ylmethyl)glutamic acid  0   *Indoles Glutamic Acid/*analogs & derivatives. Org Lett. 2000 Sep 21;2(19):2967-70
N-(4-(3-(2,4-diamino-7H-pyrrolo(2,3-d)-pyrimidin-5-yl)-1-methylpropyl)benzoyl)-gamma-fluoroglutamic acid  0   *Pyrimidines Glutamic Acid/*analogs & derivatives. Eur J Med Chem 2000 May;35(5):529-34
3,4-dihydroxyglutamic acid  0   Glutamic Acid/*analogs & derivatives Receptors, Metabotropic Glutamate/agonists. Bioorg Med Chem Lett 2000 Jan 17;10(2):129-33
beta-DADF  0   *Ribonucleotides Glutamic Acid/analogs & derivatives. J Med Chem 1999 Sep 9;42(18):3421-4
Carisolv  0   *Leucine *Lysine *Glutamic Acid Dental Cavity Preparation. Caries Res 1999 May-Jun;33(3):171-7
GW 1031  0   *Quinazolines *Glutamic Acid Thymidylate Synthase/antagonists & inhibitors. Bioconjug Chem 1999 Jan-Feb;10(1):38-48
hippuryl glutamic acid  0   Glutamic Acid/*analogs & derivatives. Protein Eng 1998 Dec;11(12):1229-34
N-methacryloyl-glutamic acid  0   *Methacrylates Glutamic Acid/*analogs & derivatives. J Dent Res 1998 Nov;77(11):1881-8
2,4-diamino-5,6,7,8-tetrahydro-7-(4'-benzoylglutamic acid)pyrido(4',3'-4,5)furo(2,3-d)pyrimidine  0   *Pyrimidines Glutamic Acid/*analogs & derivatives Tetrahydrofolate Dehydrogenase/antagonists & inhibitors. J Med Chem 1998 Apr 23;41(9):1409-16
glutamic acid-chelated iron  0   *Glutamic Acid *Iron Compounds. Zentralbl Veterinarmed A 1998 Feb;45(1):53-61
N(10)-iodoacetyl-2-desamino-2-methyl-5,8-dideazafolate  0   *Pyrimidines Glutamic Acid/*analogs & derivatives Thymidylate Synthase/antagonists & inhibitors. Biochemistry 1998 Mar 31;37(13):4535-42
N(10)-chloroacetyl-2-desamino-2-methyl-5,8-dideazafolate  0   *Pyrimidines Glutamic Acid/*analogs & derivatives Thymidylate Synthase/antagonists & inhibitors. Biochemistry 1998 Mar 31;37(13):4535-42
5-phenylpentylglutamic acid  129414-04-6   Glutamic Acid/*analogs & derivatives Stereoisomerism. Clin J Physiol 1996;39(2):131-7
1-(gamma-glutamylamino)cyclopropane-1-carboxylic acid  0   *Cyclopropanes Glutamic Acid/*analogs & derivatives. Plant Physiol 1995 Nov;109(3):917-26
leucine-methylglutamate copolymer  41385-14-2   Leucine *Dipeptides Glutamic Acid/analogs & derivatives Wound Healing. J Biomed Mater Res 1992 Jun;26(6):695-712
copoly(aspartic acid-glutamic acid)  41072-11-1   *Dipeptides Aspartic Acid Glutamic Acid. Biopolymers 1990;29(3):549

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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