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Basic-Leucine Zipper Transcription Factors

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Definition: A large superfamily of transcription factors that contain a region rich in BASIC AMINO ACID residues followed by a LEUCINE ZIPPER domain.     
Examples Activating Transcription Factors; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; CCAAT-Enhancer-Binding Proteins; Cyclic AMP Response Element-Binding Protein; Cyclic AMP Response Element-Binding Protein A; Cyclic AMP Response Element Modulator; Fos-Related Antigen-2; Interferon Regulatory Factor-1; Maf Transcription Factors; NF-E2 Transcription Factor; NF-E2-Related Factor 1; NF-E2-Related Factor 2; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1 		Other names bZIP G Box Binding Factors; Transcription Factors, bZIP; Basic Leucine Zipper Transcription Factors; bZIP Transcription Factors; bZIP Proteins; GBF bZIP Transcription Factors; bZIP G-Box Binding Factors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SMILE protein, rat  0   *Basic-Leucine Zipper Transcription Factors. J Biol Chem. 2011 Dec 9;286(49):41972-84.
SMILE protein, mouse  0   *Basic-Leucine Zipper Transcription Factors. J Biol Chem. 2011 Dec 9;286(49):41972-84.
acid response element binding factor 1, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. Mol Biol Rep. 2011 Nov;38(8):5147-59.
SARI protein, human  0   *Tumor Suppressor Proteins *Basic-Leucine Zipper Transcription Factors. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20906-11.
bZIP1 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. BMC Syst Biol 2010;4:111
BBF2H7 protein, mouse  0   *Basic-Leucine Zipper Transcription Factors. Nat Cell Biol 2009 Oct;11(10):1197-204
Xbp1 protein, Xenopus  0   *Xenopus Proteins *Basic-Leucine Zipper Transcription Factors. Development 2009 Nov;136(21):3543-8
bZIP53 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. Plant Cell 2009 Jun;21(6):1747-61
bZIP24 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. Gene 2009 May 1;436(1-2):45-55
SNFT protein, mouse  0   *Repressor Proteins *Basic-Leucine Zipper Transcription Factors Nuclear Proteins Leucine Zippers. Science 2008 Nov 14;322(5904):1097-100
bZIP60 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. Mol Genet Genomics 2008 Sep;280(3):199-210
bZIP28 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Plant Cell 2007 Dec;19(12):414-9
ZIP68 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. BMB Rep 2008 Feb 29;41(2):132-8
ZIP16 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. BMB Rep 2008 Feb 29;41(2):132-8
Yap5 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Basic-Leucine Zipper Transcription Factors. Mol Cell Biol 1997 Dec;17(12):6982-93
bZIP17 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors Membrane Proteins. Plant J 2007 Sep;51(5):897-909
CREB3L2 protein, human  0   *Basic-Leucine Zipper Transcription Factors. Mol Cell Biol 2007 Mar;27(5):1716-29
AREB1 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. Proc Natl Acad Sci U S A 2006 Feb 7;103(6):1988-93
ABF3 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. Plant Mol Biol 2005 Sep;59(2):253-67
NOC3L protein, human  0   *Nuclear Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. J Cell Sci 2004 Dec 1;117(Pt 25):6217-26
Noc3l protein, mouse  0   *Nuclear Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. J Cell Sci 2004 Dec 1;117(Pt 25):6217-26
GCN4 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Basic-Leucine Zipper Transcription Factors.
AREB3 protein, Arabidopsis thaliana  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. J Exp Bot 2005 Feb;56(412):597-603
Zip67 protein, Arabidopsis  0   *Repressor Proteins *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. J Exp Bot 2005 Feb;56(412):597-603
XMax protein, Xenopus  0   *Xenopus Proteins *Basic-Leucine Zipper Transcription Factors.
Nfil3 protein, mouse  0   *Basic-Leucine Zipper Transcription Factors.
NFIL3 protein, human  0   *Basic-Leucine Zipper Transcription Factors.
bZIP63 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors. Plant J 2004 Nov;40(3):428-38
ARR1 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Basic-Leucine Zipper Transcription Factors. Mol Biol Cell 2004 May;15(5):2049-60
BACH2 protein, human  0   *Basic-Leucine Zipper Transcription Factors Leucine Zippers.
HLF protein, human  0   *Basic-Leucine Zipper Transcription Factors Leucine Zippers.
Hlf protein, mouse  0   *Basic-Leucine Zipper Transcription Factors Leucine Zippers.
NRL protein, human  0   *Eye Proteins *Basic-Leucine Zipper Transcription Factors Transcription Factors Leucine Zippers.
E2a-Hlf fusion protein, mouse  0   *Oncogene Proteins, Fusion *Basic-Leucine Zipper Transcription Factors Leucine Zippers.
tef protein, zebrafish  0   *Zebrafish Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers.
Tef protein, mouse  0   *Basic-Leucine Zipper Transcription Factors Leucine Zippers.
TEF protein, human  0   *Basic-Leucine Zipper Transcription Factors Leucine Zippers.
AHBP-1b protein, Arabidopsis  0   *Nuclear Proteins *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers.
ATF6B protein, human  0   *Basic-Leucine Zipper Transcription Factors. Biochem J 2001 Apr 1;355(Pt 1):19-28
Bach1 protein, mouse  0   *Basic-Leucine Zipper Transcription Factors Leucine Zippers.
Nrf3 protein, mouse  0   *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Mol Cell Biol 2004 Apr;24(8);3286-94
HBZ protein, human T-cell leukemia virus type I  0   *Viral Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. J Virol 2002 Dec;76(24):12813-22
Gasz protein, rat  0   *Carrier Proteins Leucine Zippers Ankyrin Repeat Basic-Leucine Zipper Transcription Factors. Mol Endocrinol 2002 Jun;16(6):1168-84
ASZ1 protein, human  0   *Adaptor Proteins, Signal Transducing Leucine Zippers Ankyrin Repeat Basic-Leucine Zipper Transcription Factors. Mol Endocrinol 2002 Jun;16(6):1168-84
Gasz protein, mouse  0   *Adaptor Proteins, Signal Transducing Leucine Zippers Ankyrin Repeat Basic-Leucine Zipper Transcription Factors. Mol Endocrinol 2002 Jun;16(6):1168-84
EEL protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Plant Cell 2002 Jun;14(6):1391-403
CREB3L4 protein, human  0   *Nuclear Proteins *Basic-Leucine Zipper Transcription Factors Neoplasm Proteins Leucine Zippers. Cancer Res 2002 Feb 1;62(3):721-33
jun-like bZIP A protein, Aspergillus nidulans  0   *Fungal Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Curr Genet 2001 Jul;39(5-6):327-34
TBZF protein, Nicotiana tabacum  0   *Plant Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Plant Physiol 2001 Sep;127(1):23-32
proliferation arrest transcription factor, Coturnix japonica  0   *Avian Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Oncogene 2001 Sep 6;20(39):5475-83
Batf protein, mouse  0   *Basic-Leucine Zipper Transcription Factors. Eur J Immunol 2001 May;31(5):1620-7
RISBZ1 protein, Oryza sativa  0   *Plant Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. J Biol Chem 2001 Apr 27;276(17):14139-52
YAP6 protein, S cerevisiae  0   *Nuclear Proteins *Saccharomyces cerevisiae Proteins *Basic-Leucine Zipper Transcription Factors. Mol Pharmacol 2001 Mar;59(3):470-4
RSG protein, Nicotiana tabacum  0   *Plant Proteins *Repressor Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Plant Cell 2000 Jun;12(6):901-5
AP1 protein, Candida albicans  0   *Fungal Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Mol Microbiol 2000 May;36(3):618-29
SNFT protein, human  0   *Repressor Proteins *Basic-Leucine Zipper Transcription Factors Nuclear Proteins Leucine Zippers. J Immunol 2000 Jul 15;165(2):860-8
CREBZF protein, human  0   *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Nucleic Acids Res 2000 Jun 15;28(12):2446-54
ABI5 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Plant Cell 2000 Apr;12(4):599-609
TRAB1 protein, plant  0   *Plant Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. Proc Natl Acad Sci U S A 1999 Dec 21;96(26):15348-53
K8 protein, Human herpesvirus 8  0   *Repressor Proteins *Viral Proteins *Basic-Leucine Zipper Transcription Factors Leucine Zippers. J Gen Virol 1999 Mar;80( Pt 3):557-61
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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