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B7 Antigens

More information in Books or onNLM PubMed
Definition: A family of cell-surface proteins found on ANTIGEN-PRESENTING CELLS. B7 antigens are ligands for specific cell surface receptor subtypes found on T-CELLS. They play an immunomodulatory role by stimulating or inhibiting the T-CELL activation process.     
Examples Antigens, CD80; Antigens, CD86; Antigens, CD274; Inducible T-Cell Co-Stimulator Ligand; Programmed Cell Death 1 Ligand 2 Protein; V-Set Domain-Containing T-Cell Activation Inhibitor 1 		Other names Molecules, B7; Costimulatory Molecules, B7; B 7 Antigen; Antigens, B7; Antigen, B-7; B7 Molecules; B7 Costimulatory Molecules; B7 Antigen; B-7 Antigen; Antigen, B7
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
B7-H6 protein, human  0   *B7 Antigens. J Exp Med. 2009 Jul 6;206(7):1495-503
Skint2 protein, mouse  0   *B7 Antigens. J Immunol. 2007 Mar 15;178(6):3661-7
Cd276 protein, mouse  0   *B7 Antigens.
CD276 protein, human  0   *B7 Antigens. Nat Immunol 2001 Mar;2(3)269-74

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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