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Clofibric Acid

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Definition: An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.     
Pharmacological Action Anticholesteremic Agents; Hypolipidemic Agents
Examples Clofibrate
Other names Clofibrinic Acid; NSC1149; p-Chlorophenoxyisobutyric Acid; NSC 1149; p-Chlorophenoxyisobutyrate; NSC-1149; 2-(4-Chlorophenoxy)-2-methylpropionic Acid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(3-(2-(4-chlorophenyl)ethoxy)phenylthio)-2-methylpropanoic acid  0   Clofibric Acid/*analogs & derivatives. ChemMedChem 2006 Jan;1(1):49-53
1-O-clofibryl glucuronide  0   *Glucuronides Clofibric Acid/*analogs & derivatives. Chem Biol Interact. 2003 May 6;145(2):201-11
fluorofibric acid  587-11-1   Clofibric Acid/*analogs & derivatives. Xenobiotica 1996 Jul;26(7):695-707
WIN 36117  52178-87-7   Clofibric Acid/*analogs & derivatives. Xenobiotica 1996 Jul;26(7):695-707
2-(4-(4-chlorophenyl)oxy)-2-phenylacetic acid  119061-18-6   Clofibric Acid/*analogs & derivatives. Adv Exp Med Biol 1991;283:267
2-(4-(2,2-dichlorocyclopropyl)phenoxy)propane  124575-86-6   Clofibric Acid/*analogs & derivatives. Arch Pharm (Weinheim) 1989;322(10):629
2-(4-hydroxyphenoxy)-2-methylpropionic acid  67648-64-0 Propanoic acid, 2-(4-hydroxyphenoxy)-2-methyl  Clofibric Acid/*analogs & derivatives. Arch Pharm (Weinheim) 1989;322(6):337
4-chlorophenoxyisobutyric acid hydrazide  118573-64-1   Clofibric Acid/*analogs & derivatives. Rev Med Chir Soc Med Nat Iasi 1987;91(2):341
2-(4-chlorophenoxy)butyric acid  10310-19-7   Clofibric Acid/*analogs & derivatives. J Med Chem 1987;30(8):1265
moroxybrate  79990-42-4   *Morpholines Clofibric Acid/*analogs & derivatives. J Pharm Pharmacol 1987;39(1):35
ciprofibrate-coenzyme A  111900-25-5   *Acyl Coenzyme A Clofibric Acid/*analogs & derivatives. Biochem J 1986;239(3):781
clofibric acid-coenzyme A  104732-21-0   *Acyl Coenzyme A Clofibric Acid/*analogs & derivatives. Biochem J 1986;239(3):781
clofibric acid, ethanolamine drug combination  0   *Clofibric Acid *Ethanolamines Drug Combinations. Rev Med Chir Soc Med Nat Iasi 1986;90(1):156
WKLB 5  105319-50-4   Clofibric Acid/*analogs & derivatives. Pol J Pharmacol Pharm 1986;38(1):77
etofibrate 2-hydroxymethyl-2-(4-chlorophenoxy)-2-methyl propionate  31637-96-4   Clofibric Acid/*analogs & derivatives. Arzneimittelforsch 1986;36(1):92
etofibrate 2-hydroxymethylnicotinate  3612-80-4   Clofibric Acid/*analogs & derivatives. Arzneimittelforschung 1986;36(1):92
clofibrylglycylglycine  60794-10-7   Clofibric Acid/*analogs & derivatives Glycine/*analogs & derivatives. Vopr Med Khim 1984;30(2):78
clofibrylglycine  4896-55-3   Clofibric Acid/*analogs & derivatives Glycine/*analogs & derivatives. Vopr Med Khim 1984;30(2):78
dulofibrate  61887-16-9   Clofibric Acid/*analogs & derivatives. Br J Clin Pharmacol 1984;17)3):341
clofibric pyranoglucuronate  80183-07-9 D-Glucopyranuronic acid, 1-(2-(4-chlorophenoxy)-2-methylpropanoate)  Clofibric Acid/*analogs & derivatives. Life Sci 1981;28(18):2077
clofibric furanoglucuronate  80106-54-3 D-Glucofuranuronic acid, 1-(2-(4-chlorophenoxy)-2-methylpropanoate)  Clofibric Acid/*analogs & derivatives. Life Sci 1981;28(18):2077
pirifibrate  21550-30-1 Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, (6-(hydroxymethyl)-2-pyridinyl)methyl ester, hydrochloride  *Clofibric Acid *Propionates. Clin Ther 1980;3(3):219
plafibride  63394-05-8   Clofibric Acid/*analogs & derivatives.
Pharma Action Hypolipidemic Agents ; Platelet Aggregation Inhibitors
Arch Farmacol Toxicol 4(1):132-139;1978
magnesium chlorphenoxyisobutyrate, mesoinositol hexanicotinate drug combination  76847-54-6   *Clofibric Acid *Nicotinic Acids Drug Combinations Inositol/*analogs & derivatives. Arzneim Forsch 1979;29(10):1621; Int J Clin Pharmacol Biopharm 15(12):585;1977
etofibrate  31637-97-5 2-(p-chlorophenoxy)-2-methylpropionic acid 2- (nicotinoyloxy)ethyl ester  Clofibric Acid/*analogs & derivatives.
Pharma Action Anticholesteremic Agents ; Hypolipidemic Agents
Arch Farm Tox 4(1):25-28;1978; Arch Pharmacol Toxicol 5(1):29;1979; Arzenim Forsch 24(12):1990;1974; Dtsch Med Wochenschr 101(31):1168;1976; Fortsch Med 94(13):785;1976; Gen Pharmacol 10(3):215;l979; Gen Pharmacol 1979;10(4):315; Gen Pharmacol 1979;10(6):455; Int J Clin Pharmacol Biopharm 1979;17(12):498; Med Klin 1979;74(51-2):1953; Med Klin 73(2):60;1978; Minerva Med 1980;71(4):273; MMW 1980;122(3):95
alfibrate  24818-79-9 hydroxy bis-(2-(p-chlorophenoxy)isobutyric acid)-aluminum  Clofibric Acid/*analogs & derivatives. Dtsch Med Wochenschr 99(26):1392;1974; Jap J Pharmacol 23(3):281;1973; Schweitz Med Wochenschr 106(39):1301;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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