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Norleucine

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Definition: An unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to METHIONINE, however it does not contain SULFUR.     
Examples Diazooxonorleucine 		Other names Norleucine, L Isomer; L-Isomer Norleucine; Norleucine, L-Isomer
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
6-(3-hydroxy-4-oxo-2-methyl-4(1H)-pyridin-1-yl)norleucine  0   *Pyridones Norleucine/*analogs & derivatives. Eur J Pharm Biopharm 2011 May;78(1):75-82
N-palmitoylnorleucinol 1-phosphate  0   *Phosphoric Acid Esters Norleucine/*analogs & derivatives Apoptosis Stereoisomerism. Biochem J 2002 Dec 1;368(Pt 2):447-59
N-dansylnorleucine  0   *Dansyl Compounds Norleucine/*analogs & derivatives. Anal Sci 2002 Jul;18(7):823-5
norleucine p-nitroanilide  0   *Anilides Norleucine/*analogs & derivatives. Biochemistry 2001 Sep 4;40(35):10645-54
N(6)-aminocaproylnorleucine  0   Norleucine/*analogs & derivatives. Acta Pol Pharm 1996 May-Jun;53(3):221-3
6-pyrrolylnorleucine  0   Norleucine/*analogs & derivatives. Lipids 1995 Jun;30(6):477-83
alpha,alpha-di-n-butylglycine  7597-66-2   Norleucine/*analogs & derivatives. Biopolymers 1995 Jan;35(1):1-9
monomethoxypolyethylene glycol conjugated norleucine  0   *Norleucine *Polyethylene Glycols. Appl Biochem Biotechnol 1991Dec;31(3):213-22
2-formyl-5-(hydroxymethyl)pyrrole-1-norleucine  74509-14-1   *Pyrroles Norleucine/*analogs & derivatives Glycosylation End Products, Advanced. J Chromatogr 1989;463(1):119
BW 175  120716-81-6 L-Arabinitol, 1-cyclohexyl-1,2,5-trideoxy-2-((2-((2-((ethylsulfonyl)methyl)-3-(1-naphthalenyl)-1-oxopropyl)amino)-1-oxohexyl)amino)-5-(4-morpholinyl)-, (S-(R*,R*))  *Morpholines Norleucine/*analogs & derivatives Renin/antagonists & inhibitors. Biochem Biophys Res Commun 1989;159(3):999
indospicine  16377-00-7   Norleucine/*analogs & derivatives. Aust Vet J 1988;65(11):337
2-amino-6-phosphonohexanoic acid  78944-89-5   Norleucine/*analogs & derivatives. Neurosci Lett 1984;49(2):217
beta-methylnorleucine  28116-92-9 L-Norleucine, 3-methyl-, erythro  Norleucine/*analogs & derivatives. J Antibiot (Tokyo) 1981;34(10):1278
homoisoleucine  3570-21-6 Norleucine, 4-methyl  Norleucine/*analogs & derivatives. J Biochem 80:333;1976
epsilon-hydroxynorleucine  305-77-1 6-hydroxynorleucine  Norleucine/*analogs & derivatives. Biochem Biophys Res Commun 47(4):760;1972
N-diazoacetylnorleucine methyl ester  7013-09-4   Norleucine/*analogs & derivatives. Biochem J 124(4):673;1971; Biochem J 151(2):319;1975; Biochem Pharmacol 27:827;1978; Hoppe Seylers Z Physiol Chem 260(6):791;1979; J Biochem (Tokyo) 80(1):61;1976; J Biochem (Tokyo) 80(5):975;1976; J Biochem (Tokyo) 80:497;1976; J Biochem (Tokyo) 81:1739;1977; J Biochem (Tokyo) 83(2):441;1978; J Biochem (Tokyo) 84(6):1593;1978; Mol Basis Malignancy Q2 202 M718:97;1976; Z Parasitenkd 1979;61(1):83

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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