Definition: A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
do not confuse with RENNIN see CHYMOSIN
Other names Renin, Inactive; Renin, Big; Pre Prorenin; Angiotensin Forming Enzyme; Prorenin; Preprorenin; Pre-Prorenin; Inactive Renin; Cryorenin; Big Renin; Angiotensinogenase; Angiotensin-Forming Enzyme