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Tropolone

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Definition: A seven-membered aromatic ring compound. It is structurally related to a number of naturally occurring antifungal compounds (ANTIFUNGAL AGENTS).     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
miltipolone  0   *Diterpenes Tropolone/*analogs & derivatives. Eur J Med Chem 2011 Apr;46(4):1117-21
alpha-thujaplicin  0   *Monoterpenes Tropolone/*analogs & derivatives Monophenol Monooxygenase/antagonists & inhibitors. Biol Pharm Bull 2001 Jun;24(6):607-11
5-methyltropolone  0   Tropolone/*analogs & derivatives. J Chem Phys. 2010 Nov 14;133(18):184307
pernambucone  0   Tropolone/*analogs & derivatives. Pharmazie. 2009 May;64(5):350-1
4-isopropyl-2-(2-hydroxyanilino)tropone  0   Tropolone/*analogs & derivatives. Anticancer Res 2009 Apr;29(4):1123-30
7-bromo-2-(4-hydroxyanilino)tropone  0   Tropolone/*analogs & derivatives. Anticancer Res 2009 Apr;29(4):1123-30
5-(4-ethoxyphenylazo)tropolone  0   *Azo Compounds Tropolone/*analogs & derivatives. J Oleo Sci 2008;57(9):513-9
N,N'-di-(tropon-2-yl)piperazine  0   *Piperazines Tropolone/*analogs & derivatives. J Oleo Sci 2008;57(9):513-9
2-aminotropone  0   Tropolone/*analogs & derivatives. J Oleo Sci 2008;57(9):513-9
3-hydroxy-5,6-dimethoxy-2-methylcyclohepta-2,4,6-trien-1-one  0   Tropolone/*analogs & derivatives. Fitoterapia. 2008 Apr;79(3):236-7
noreupenifeldin  0   Tropolone/*analogs & derivatives. J Nat Prod 2008 Mar;71(3):457-9
troposulfenin  0   *Sulfhydryl Compounds Tropolone/*analogs & derivatives. J Org Chem. 2008 Jan 4;73(1):280-3
tropodithietic acid  0   Tropolone/*analogs & derivatives. J Org Chem. 2008 Jan 4;73(1):280-3
aminotroponiminate  0   *Imines Tropolone/*analogs & derivatives. Inorg Chem 2007 May 28;46(11):4599-604
aminotroponate  0   Tropolone/*analogs & derivatives. Inorg Chem 2007 May 28;46(11):4599-604
5-azatropolone  0   *Aza Compounds Tropolone/*analogs & derivatives. J Phys Chem A. 2006 Feb 2;110(4):1600-7
sepedonin  0   Tropolone/*analogs & derivatives. Environ Sci 2006;13(5):251-6
3,7-dibromo-5-morpholinomethyltropolone  0   Tropolone/*analogs & derivatives. Biochem Biophys Res Commun 2006 Mar 10;341(2):641-7
4-acetyltropolone  0   Tropolone/*analogs & derivatives. Biol Pharm Bull. 2004 Oct;27(10):1666-9
beta-thujaplicinol  0   Tropolone/*analogs & derivatives Ribonuclease H/antagonists & inhibitors HIV Reverse Transcriptase/antagonists & inhibitors. Nucleic Acids Res 2005;33(4):1249-56
cordytropolone  0   *Furans Tropolone/*analogs & derivatives. J Antibiot (Tokyo) 2001 Sep;54(9):751-2
2-hydroxy-5-isopropyl- 2,4,6-cycloheptatrienone  0   *Monoterpenes Tropolone/*analogs & derivatives. Antiviral Res 1998 Aug;39(2):89-100
U 92798  0   *Azepines Tropolone/*analogs & derivatives. Neurosurgery 1994 Feb;34(2):332-8
U 92032  142223-92-5 2,4,6-Cycloheptatrien-1-one, 7-((4-(bis(4-fluorophenyl)methyl)-1-piperazinyl)methyl)-2-((2-hydroxyethyl)amino)-4-(1-methylethyl)  *Piperazines Tropolone/*analogs & derivatives. J Pharmacol Exp Ther 1994 Mar;268(3):1135-42
pareirubrine B  152845-78-8   *Isoquinolines Tropolone/*analogs & derivatives Alkaloids Plant Extracts. Chem Pharm Bull (Tokyo) 1993 Aug;41(8):1418-22
pareirubrine A  147044-68-6 10H-Azuleno(1,2,3-ij)isoquinolin-10-one, 9-hydroxy-4,5,6,11-tetramethoxy  *Isoquinolines Phorbols Tropolone/*analogs & derivatives Alkaloids Plant Extracts. Chem Pharm Bull (Tokyo) 1993 Aug;41(8):1418-22
eupenifeldin  151803-45-1   Tropolone/analogs & derivatives. J Antibiot (Tokyo) 1993 Jul;46(7):1082-8
JCI 3661  92832-17-2 2,4,6-Cycloheptatrien-1-one, 3,3'-((4-methoxyphenyl)methylene)bis(2-hydroxy-6-(1-methylethyl))  Tropolone/*analogs & derivatives. Jpn J Cancer Res 1992 Jun;83(6):661-8
3,7-dihydroxytropolone  85233-29-0 2,4,6-Cycloheptatrien-1-one, 2,3,4-trihydroxy  Tropolone/analogs & derivatives. J Antibit (Tokyo) 1988;41(7):862
3-methoxytropolone  65425-62-9   Tropolone/*analogs & derivatives. J Antibiot (Tokyo) 1986;39(4):589
indium tris(tropolonate)  14283-79-5   *Organometallic Compounds Tropolone/*analogs & derivatives Indium Radioisotopes. Clin Exp Immunol 1984;58(3):737
thiotropocin  89550-93-6   Tropolone/analogs & derivatives. J Antibiot (Tokyo) 1984;37(11):1294
7-iodohinokitiol  30595-86-9 2,4,6-Cycloheptatrien-1-one, 2-hydroxy-7-iodo-4-(1-methylethyl)-, (S)  Tropolone/*analogs & derivatives. Yakugaku Zasshi 1983;103(12):1303
2-methoxytropolone  2161-40-2   Tropolone/*analogs & derivatives. Biochemistry 1982;21(25):6465
7-hydroxytropolone  33739-50-3 2,4,6-Cycloheptatrien-1-one, 2,7-dihydroxy  Tropolone/*analogs & derivatives. Antimicrob Agents Chemother 1982;22(5):824
2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone  60423-21-4   Tropolone/*analogs & derivatives.
Pharma Action Tubulin Modulators 		J Biol Chem 1981;256(12):6241
N-troponyloxamic acid  65425-79-8 Acetic acid, oxo((7-oxo-1,3,5-cycloheptatrien-1-yl)amino)  Tropolone/*analogs & derivatives. J Med Chem 22(10):1186;1979
methoxydinitrotropone  0   Tropolone/*analogs & derivatives. Boll Soc Ital Biol Sper 53(23):2238;1977
beta-thujaplicin  499-44-5   *Monoterpenes Tropolone/*analogs & derivatives.
Pharma Action Anti-Infective Agents ; Antineoplastic Agents, Phytogenic ; Iron Chelating Agents 		Br J Pharmacol 65(2):175;1979; J Bacteriol 1980;141(1):164; Naunyn Schmiedebergs Arch Pharmacol 307(3):235;1979; Nippon Shishubyo Gakkai Kaishi 19(4):413;1977
3-isopropyl-5,7-dipiperidinomethyltropolone  41620-96-6 2-hydroxy-3-(1-methylethyl)-5,7-bis(1- piperidinylmethyl)-2,4,6-cycloheptatrien-1-one dihydrochloride  Tropolone/*analogs & derivatives. J Pharm Soc Jap 93(5):547;1973
tropone  539-80-0 2,4,6-cycloheptatrien-1-one  Tropolone/*analogs & derivatives.
3-isopropyl-5,7-dimorpholinomethyltropolone  34723-12-1   Tropolone/*analogs & derivatives. J Pharm Soc Jap 92(5):570;1972

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