encyclopedia of medical concepts
ψ 

Fluoroquinolones

More information in Books or onNLM PubMed
Definition: A group of QUINOLONES with at least one fluorine atom and a piperazinyl group.     
Pharmacological Action Anti-Bacterial Agents; Nucleic Acid Synthesis Inhibitors
Examples Ciprofloxacin; Enoxacin; Norfloxacin; Ofloxacin; Pefloxacin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7-(3-aminopyrrolo(3,4-c)pyrazol-5(2H,4H,6H)-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid  0   *Fluoroquinolones Anti-Bacterial Agents. Arch Pharm (Weinheim). 2011 Aug;344(8):523-9
finafloxacin  0   *Fluoroquinolones Anti-Infective Agents, Urinary. Antimicrob Agents Chemother 2010 Apr;54(4):1613-5
4-((2-cyclobutyl-1H-imidazo(4,5-b)pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one  0   *Pyrazines *Fluoroquinolones Nitric Oxide Synthase Type II/antagonists & inhibitors Nitric Oxide Synthase Type I/antagonists & inhibitors. J Med Chem 2009 May 14;52(9):3047-62
9-(4-aminopiperazin-1-yl)-8-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-azaphenalene-5-carboxylic acid  0   *Piperazines *Fluoroquinolones. J Med Chem 2010 Aug 12;53(15):5684-9
7-(3-(2-amino-1-fluoroethylidene)-1-piperidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid  0   *Fluoroquinolones. Antimicrob Agents Chemother 2010 May;54(5):1955-64
sinafloxacin  0   *Fluoroquinolones. Food Chem Toxicol. 2008 Feb;46(2):575-80
CPUY013 compound  0   *Oxazoles *Fluoroquinolones DNA Topoisomerases, Type I/antagonists & inhibitors. Yao Xue Xue Bao 2008 Aug;43(8):811-8
N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylthiazole-5-carboxamide  0   *Thiazoles *Fluoroquinolones Nitric Oxide Synthase Type II/antagonists & inhibitors. Mol Pharmacol 2009 Jul;76(1):153-62
7-(7-amino-7-methyl-5-azaspiro(2.4)heptan-5-yl)-6-fluoro-1-(2-fluoro-1-cyclopropyl)-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid  0   *Aminopyridines *Fluoroquinolones. J Antimicrob Chemother 2008 Jul;62(1):98-104
7-((3R)-aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid  0   *Azepines *Fluoroquinolones. J Ocul Pharmacol Ther. 2007 Jun;23(3):243-56BESIVANCE
WCK 1152  0   *Piperidines *Fluoroquinolones. J Antimicrob Chemother. 2005 Dec;56(6):1130-3
WCK 1153  0   *Piperidines *Fluoroquinolones. J Antimicrob Chemother. 2005 Dec;56(6):1130-3
pradofloxacin  0   *Fluoroquinolones. Antimicrob Agents Chemother 2005 Oct;49(10):4166-73
fluoroquinolone-pyrrolo(2,1-c)(1,4)benzodiazepine  0   *Benzodiazepines *Fluoroquinolones. Bioorg Med Chem. 2005 Mar 15;13(6):2021-9
borocin  0   *Fluoroquinolones. Tsitol Genet. 2004 Nov-Dec;38(6):23-7
7-amino-1-(5-amino-2,4-difluorophenyl)-6-fluoro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid  0   *Fluoroquinolones. Nihon Hansenbyo Gakkai Zasshi 2005 Feb;74(1):43-8
1-(5-amino-2,4-difluorophenyl)-6-fluoro-8-methyl-7-methylamino-4-oxo-1,4-dihydroquinoline-3-carboxylic acid  0   *Fluoroquinolones. Nihon Hansenbyo Gakkai Zasshi 2005 Feb;74(1):43-8
CQ-M-EPCA  0   *Fluoroquinolones. Int J Pharm 2004 Sep 10;282(1-2):87-94
WCK 771  0   *Fluoroquinolones. Antimicrob Agents Chemother. 2004 Aug;48(8):3188-92
cadrofloxacin  0   *Fluoroquinolones. Jpn J Antibiot 2004 Feb;57(1):118-23
DK-507k  0   *Fluoroquinolones. Antimicrob Agents Chemother. 2003 Dec;47(12):3750-9
DW-224a  0   *Fluoroquinolones. Biol Pharm Bull. 2003 Jun;26(6):832-9
1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid  0   *Fluoroquinolones. Yao Xue Xue Bao 2002 Jun;37(6):462-4
Y904  0   *Morpholines *Fluoroquinolones. J Infect Chemother 2003 Jun;9(2):165-71
AM-1121  0   *Fluoroquinolones. Antimicrob Agents Chemother 2001 Oct;45(10):2755-64
7(3-amino-2-methyl-1-azetidinyl)-1-(2,4- difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-3-quinolinecarboxylic acid tosylate  0   *Fluoroquinolones. Arzneimittelforschung 2001 51(5):425-32
garenoxacin  0   *Fluoroquinolones. Antimicrob Agents Chemother. 2000 Dec;44(12):3351-6
fluoroquinoline K-37  0   *Fluoroquinolones. Virology 2000 Jul 5;272(2):402-8
WQ 3034  0   *Fluoroquinolones. Antimicrob Agents Chemother 2000 Feb;44(2):283-6
AF 3013  0   *Fluoroquinolones. Drugs Exp Clin Res 1999;25(1):1-11
K-12, fluoroquinolone  0   *Piperazines *Fluoroquinolones. Antivir Chem Chemother 1998 Sep;9(5):403-11
S 34109  0   *Pyrrolidines *Fluoroquinolones. Bioorg Med Chem Lett 1998 Oct 20;8(20):2833-8
T 3762  0   *Fluoroquinolones. Biol Pharm Bull 1998 May;21(5):456-60
Y 688  0   *Fluoroquinolones. Antimicrob Agents Chemother 1998 Feb;42(2):419-24
alatrofloxacin  157605-25-9   *Fluoroquinolones.
Pharma Action Anti-Infective Agents 		Antimicrob Agents Chemother 1997 Jun;41(6):1298-300TROVAN PRESERVATIVE FREE; TROVAN
olamufloxacin  0   *Fluoroquinolones. Antimicrob Agents Chemother 1997 Apr;41(4):857-9
premafloxacin  143383-65-7   *Pyrroles *Fluoroquinolones. J Antimicrob Chemother 1996 Oct;38(4):742-4
gemifloxacin  175463-14-6   *Naphthyridines *Fluoroquinolones.
Pharma Action Anti-Bacterial Agents 		Antimicrob Agents Chemother 1996 Jun;40(6):1564-8GEMIFLOXACIN MESYLATE; FACTIVE
FA-103  0   *Azepines *Fluoroquinolones. Jpn J Antibiot 1995 Dec;48(12):1891
DW-116  0   *Piperazines *Fluoroquinolones. Drugs 1995;49 Suppl 2:323-5
CFC 222  0   *Fluoroquinolones. Drugs 1995;49 Suppl 2:321-2
CS 940  0   *Piperazines *Fluoroquinolones. Antimicrob Agents Chemother 1995 Oct;39(10):2325-30
cifran  0   *Fluoroquinolones. Khirurgiia (Mosk) 1994 Nov;(11):34-5
NSFQ-105  0   *Fluoroquinolones. J Antimicrob Chemother 1994 Aug;34(2):261-5
NSFQ-104  0   *Fluoroquinolones. J Antimicrob Chemother 1994 Aug;34(2):261-5
A 80556  114676-82-3   *Fluoroquinolones. Antimicrob Agents Chemother 1994 May;38(5):1071-8
PD 138312  107334-06-5   *Naphthyridines *Fluoroquinolones DNA Topoisomerases, Type II/antagonists & inhibitors. Antimicrob Agents Chemother 1993 Dec;37(12):2563-70
P-floxacin  0   *Fluoroquinolones. Indian Pediatr 1993 May;30(5):718
DV 7751a  151390-79-3 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 10-(8-amino-6-azaspiro(3.4)oct-6-yl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S-(R*,R*))  *Fluoroquinolones. Antimicrob Agents Chemother 1993 Oct;37(10):2112-8
1,2-dihydro-9,1-(epoxymethano)-7-fluoro-8-(4-methyl-1-piperazinyl)-5-oxo-5H-thiazolo(3,2-a)quinoline-4-carboxylic acid  0   *Fluoroquinolones. J Med Chem 1993 Oct 15;36(21):3148-53
1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxyic acid  123942-05-2   *Fluoroquinolones DNA Topoisomerases, Type II/antagonists & inhibitors. J Med Chem 1993 Sep 17;36(19):2801-9
BO 2367  145902-81-4   *Fluoroquinolones. Jpn J Cancer 1993 Jul;84(7):800-6
E-4868  141725-88-4 3-Quinolinecarboxylic acid, 7-(3-amino-2-methyl-1-azetidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, (2S-trans)  *Fluoroquinolones. Antimicrob Agents Chemother Apr;37(4):868-74
PD 140248  147208-55-7   *Naphthyridines *Fluoroquinolones. J Med Chem 1993 Apr 2;36(7):871-82
BMY 45243  147740-98-5   *Naphthyridines *Fluoroquinolones. Drugs Exp Clin Res 1992;18(7):291-4
marbofloxacin  115550-35-1   *Fluoroquinolones.
Pharma Action Anti-Bacterial Agents 		Zentralbl Veterinarmed (A) 1993 Feb;40(1):73-9
trovafloxacin  146836-84-2   *Naphthyridines *Fluoroquinolones.
Pharma Action Anti-Infective Agents 		Antimicrob Agents Chemother 1993 Feb;37(2):349-53
Bay Y3118  144194-96-7 3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-, monohydrochloride, (4aS-cis)  *Fluoroquinolones. Chemotherapy 1992;38(6):376-87
nefloxacin  146239-82-9   *Fluoroquinolones. Chin Med J (Engl) 1992 Jun;105(6):500-5
pazufloxacin  127045-41-4 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S)  *Oxazines *Fluoroquinolones.
Pharma Action Antitubercular Agents 		Antimicrob Agents Chemother 1992 Oct;36(10):2293-2303
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy