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Oxazines

More information in Books or onNLM PubMed
Definition: Six-membered heterocycles containing an oxygen and a nitrogen.     
Examples Benzoxazines; Ifosfamide; Morpholines
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7-(p-acetoxyphenylmethyloxy)-3H-phenoxazin-3-one  0   *Acetates *Oxazines. Analyst. 2012 Feb 7;137(3):716-21.
N,N-diethyl-5-((4-methoxyphenyl)imino)-5H-benzo(a)phenoxazin-9-amine  0   *Oxazines. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5804-7.
lacmoid  0   *Oxazines Surface-Active Agents.
O4 compound  0   *Oxazines. Nat Chem Biol. 2012 Jan;8(1):93-101
dihydroresorufin  0   *Oxazines. Arch Androl. 1994 Sep-Oct;33(2):71-5.
SSJ 183  0   *Oxazines *Pyridines. Bioorg Med Chem 2011 Jul 1;19(13):4144-7
2-morpholin-7-(pyridin-2-ylmethoxy)-4H-naphth(2,1-e)-1,3-oxazin-4-one  0   *Morpholines *Oxazines. Bioorg Med Chem 2011 Jul 1;19(13):3983-94
spironaphthoxazine  0   *Oxazines *Spiro Compounds. Bioorg Med Chem 2011 Feb 1;19(3):1030-40
2-ethoxy-4,5-diphenyl-1,3-oxazine-6-one  0   *Oxazines. Eur J Pharmacol. 2011 May 11;658(2-3):84-90
3-(diethylamino)-7-(1,4-dioxa-7,13-dithia-10-azacyclopentadecan-10-yl)phenoxazin-5-ium chloride  0   *Oxazines. Org Lett. 2011 May 20;13(10):2710-3
CH 4987655  0   *Benzamides *Oxazines. Bioorg Med Chem Lett 2011 Mar 15;21(6):1795-801
CX-614  0   *Oxazines. Org Lett. 2011 Mar 18;13(6):1426-8
5,6-dihydro-4H-1,3-oxazine hydrobromide  0   *Oxazines. J Org Chem. 2011 Jan 21;76(2):680-3
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine  0   *Oxazines. Proc Natl Acad Sci U S A 2010 Sep 28;107(39):16982-7
pitucamycin  0   *Oxazines. J Nat Prod. 2010 Sep 24;73(9):1461-4
chandrananimycin D  0   *Oxazines. J Nat Prod. 2010 Sep 24;73(9):1461-4
5,6-dihydro-2H-5-phenyloxazin-2-one  0   *Oxazines. Org Lett 2010 Mar 19;12(6):1256-9
resorufin alpha-D-mannopyranoside  0   *Mannosides *Oxazines. Anal Biochem. 2010 Apr 1;399(1):7-12
1,3,3-trimethyl-5'-(2-benzothiazolyl)-spiroindoline-2,3'-naphtho(2,1-b)(1,4) oxazine  0   *Oxazines *Spiro Compounds. Phys Chem Chem Phys. 2009 Jul 21;11(27):5608-14
6,8-dichloro-2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine  0   *Oxazines. Toxicol In Vitro. 2009 Sep;23(6):1039-46
Nile blue-based chemodosimeter  0   *Oxazines *Phenylthiourea. Org Lett 2009 May 21;11(10):2101-4
(4-(4-(4-amino-7,7-dimethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)phenyl)bicyclo(2.2.2)oct-1-yl)acetic acid  0   *Oxazines *Pyrimidines Diacylglycerol O-Acyltransferase/antagonists & inhibitors. J Med Chem 2009 Mar 26;52(6):1558-68
6-chloro-9-nitro-5-oxo-5H-benzo(a)phenoxazine  0   *Oxazines. Mol Cancer Ther 2009 Feb;8(2):333-41
ZK 234238  0   *Oxazines Nitric Oxide Synthase Type I/antagonists & inhibitors. Crit Care Med 2009 Jan;37(1):208-14
Basic Blue 3  0   *Oxazines Coloring Agents. J Hazard Mater 2008 May 1;153(1-2):96-106
7-epi-FR900482  0   *Oxazines. Org Lett 2008 Apr 3;10(7):1369-72
5,9-diaminodibenzo(a,j)phenoxazine  0   *Oxazines. J Fluoresc 2008 Mar;18(2):513-8
7-hydroxy-(8-oxazine-2-one)-quinoline  0   *Oxazines *Quinolines. Phys Chem Chem Phys. 2008 Mar 7;10(9):1243-7
resorufin-beta-D-cellobioside  0   *Disaccharides *Oxazines. Anal Biochem. 2007 Dec 15;371(2):146-53
1,3-diaza-2-oxophenoxazine  0   *Oxazines. Nucleic Acids Res 2008 Jan;36(1):157-67
Bay 65-1942  0   *Oxazines *Pyridines. Am J Physiol Heart Circ Physiol 2007 Oct;293(4):H2248-53
R788 compound  0   *Oxazines *Pyridines Prodrugs. Clin Immunol 2007 Sep;124(3):244-57
3,4-dihydro-2H-benzo(1,4)oxazine  0   *Oxazines. Bioorg Med Chem Lett 2007 Jun 15;17(12):3504-7
elloxazinone B  0   *Oxazines. J Antibiot (Tokyo) 2007 Apr;60(4):277-84
elloxazinone A  0   *Oxazines. J Antibiot (Tokyo) 2007 Apr;60(4):277-84
N-methyl-P (6-methyl-3,4-dihydro-8H-pyrimido(4,5-c)(1,2)oxazin-7-one)  0   *Oxazines *Pyrimidines. J Phys Chem A 2005 Nov 17;109(45):10199-207
1,2,3,6-tetrahydro-2-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluoromethyl)-7H-(1,4)oxazino(3,2-g)quinolin-7-one  0   *Oxazines *Quinolones. J Med Chem 2007 May 17;50(10):2486-96
Nile Red beta-C-2'-deoxyriboside  0   *Oxazines Deoxyribose/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2005;(49):155-6
1H-thieno(3,2-d)(1,3)oxazine-2,4-dione  0   *Oxazines. J Org Chem. 2007 Mar 30;72(7):2662-5
efavirenz, emtricitabine, tenofovir disoproxil fumarate drug combination  0   *Oxazines *Phosphonic Acids Adenine/*analogs & derivatives Deoxycytidine/*analogs & derivatives Drug Combinations.
Pharma Action Reverse Transcriptase Inhibitors 		Med Lett Drugs Ther 2006 Sep 25;48(1244):78-9EFAVIRENZ/LAMIVUDINE/TENOFOVIR DISOPROXIL FUMARATE; ATRIPLA; EFAVIRENZ; EMTRICITABINE; TENOFOVIR DISOPROXIL FUMARATE
buxozine C  0   *Oxazines *Triterpenes Alkaloids. Arch Pharm (Weinheim) 2006 Dec;339(12):675-6
yunnandaphnine E  0   *Oxazines. J Nat Prod 2006 Dec;69(12):1745-8
N(1),N(6)-bis(2,2,6,6-tetrakis(trifluoromethyl)-3,6-dihydro-2H-1,3,5-oxadiazine-4-yl)-1,6-hexanediamine  0   *Oxazines. Antibiot Khimioter 2005;50(8-9):10-4
9-(iodomethylcarbonyloxy)(methyl)amino-5H-benz(a)phenoxazin-5-one  0   *Oxazines. Bioconjug Chem 2006 Mar-Apr;17(2):387-92
9-diethylamino-2-(iodomethylcarbonylaminoethoxy)-5H-benz(a)phenoxazin-5-one  0   *Oxazines. Bioconjug Chem 2006 Mar-Apr;17(2):387-92
N4-(2,2-dimethyl-3-oxo-4H-pyrid(1,4)oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine  0   *Oxazines *Pyridines. J Pharmacol Exp Ther 2006 May;317(2):571-8
MR121 oxazine fluorophore  0   *Oxazines. Nucleic Acids Res. 2006;34(9):2516-27
N-decarbomethoxyllated JW062  0   *Oxazines. Neurotoxicology 2006 Mar;27(2):237-44
oxaziclomefone  0   *Oxazines. Ann Bot (Lond). 2005 Nov;96(6):1097-107
7-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-5-(3-piperidinyl)-1,4-dihydro-2H-pyrido(2,3-d)(1,3)oxazin-2-one  0   *Oxazines *Pyridines. Br J Pharmacol 2005 May;145(2):178-92
NSC-643735  0   *Oxazines. Cancer Res 2005 Jun 1;65(11):4918-28
1,2-o-dilauryl-rac-glycero glutaric acid-(6'-methyl resorufin) ester  0   *Glutarates *Oxazines. Vet Clin Pathol. 2005;34(1):39-43
5,9-bis(diethylamino)-10-methylbenzo(a)phenoxazonium  0   *Oxazines. J Med Chem 2005 May 19;48(10):3471-3
1,3,4-oxadiazino(6,5-b)indole  0   *Indoles *Oxazines. Nucleosides Nucleotides Nucleic Acids. 2004;23(12):1825-32
2-(4-(8-methyl-2-oxo-4H-benzo(d)(1,3)oxazin-1-yl)piperidin-1-yl)-N-(9-oxo-9H-fluoren-3-yl)acetamide  0   *Fluorenes *Oxazines. J Med Chem 2005 Mar 24;48(6):2080-92
LFA 878  0   *Naphthalenes *Oxazines. J Biol Chem 2004 Nov 5;279(45):46764-71
7-(3-aminopyrrol-1-yl)-11-carboxy-8-fluoro-10-oxoquino(2,3,4-ij)(1,4)benzoxazino(6,7-b)benzofuran  0   *Oxazines *Quinolines. Biochemistry 2004 Sep 28;43(38):11953-8
N-(1-(4-cyclopropylmethyl-3,4-dihydro-2H-benzo(1,4)oxazin-6-yl)ethyl)-3-(2-fluorophenyl)acrylamide  0   *Acrylamides *Oxazines. Bioorg Med Chem Lett 2004 Apr 19;14(8):1991-5
(aspartyl-glutamyl-valyl-aspartate)2-cresyl violet  0   *Oligopeptides *Oxazines. Biotechniques. 2003 Nov;35(5):1080-5
1-((2-(acetylamino)-2-carboxyethyl)thio)-2-amino-3-oxo-8-carboxyl-3H-phenoxiazine  0   *Oxazines. J Antibiot (Tokyo). 2004 Mar;57(3):218-23
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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