encyclopedia of medical concepts
ψ 

Pyrazolones

More information in Books or onNLM PubMed
Definition: Compounds with a five-membered heterocyclic ring with two nitrogens and a keto OXYGEN. Some are inhibitors of TNF-ALPHA production.     
Examples Aminopyrine; Antipyrine; Phenylbutazone 		Other names Pyrazolin 5 Ones; Pyrazolin-5-Ones
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(3'-iodophenyl)-3-methy-2-pyrazolin-5-one  0   *Pyrazolones. Chem Pharm Bull (Tokyo). 2010;58(8):1020-5
1-(4-isopropyl)phenyl-3-methyl-5-pyrazolone  0   *Pyrazolones. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 May 1;878(15-16):1135-44
N-(4-chlorophenyl)-N'-(5-isopropyl-1-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea  0   *Pyrazolones Urea/*analogs & derivatives. J Pharmacol Sci. 2009 Nov;111(3):317-21
4-benzoyl-3-methyl-1-phenyl-pyrazol-5-one  0   *Pyrazolones. Bioorg Med Chem. 2009 Sep 1;17(17):6166-72
pyrrolo(3,4-c)pyrazole-4,6-dione  0   *Pyrroles *Pyrazolones. Molecules. 2008;13(4):1011-24
1-(2-naphthyl)-3-methyl-5-pyrazolone  0   *Naphthalenes *Pyrazolones. Anal Chim Acta. 2008 Feb 18;609(1):66-75
CC 401  0   *Pyrazolones JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors. Transplantation 2004 Aug 15;78(3):324-32
3-methyl-1-(pyridin-2-yl)-5-pyrazolone  0   *Pyridines *Pyrazolones. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5939-42
3-methyl-4-(O-methyl-oximino)-1-phenylpyrazolin-5-one  0   *Pyrazolones. Eur J Pharmacol. 2005 Dec 28;528(1-3):37-42
1,3-diphenyl-4-(4'-fluro)benzal-5-pyrazolone-4-ethyl thiosemicarbazone  0   *Thiosemicarbazones *Pyrazolones. Spectrochim Acta A Mol Biomol Spectrosc. 2005 Sep;61(11-12):2590-4
nostocine A  0   *Triazines *Pyrazolones Pigments, Biological. J Biotechnol 2004 May 13;110(1):29-35
1-phenyl-2,3-dimethyl-4-iodopyrazolone  0   *Iodine Compounds *Pyrazolones. Klin Med (Mosk) 2002;80(4):52-4
4-(4-chlorophenylazo)-3-methyl-1-(2-hydroxy-3-morphilinopropan-1-yl)-2-pyrazolin-5-one  0   *Azo Compounds *Pyrazolones. Spectrochim Acta A Mol Biomol Spectrosc 2001 Oct;57(12):2359-65
BTS 71 412  0   *Pyrazolones. Int J Immunopharmacol 1995 May;17(5):357-66
dihydrotrifluoromethylbenzothiopyranopyrazolone  0   *Pyrazolones. Br J Dermatol 1995 Jan;132(1):144-8
3-methylpyrazolin-5(4H)-one-4-(3'-methoxy-4'-(2'',3'',4'',6''-tetra-O-acetylglycopyranosyl))benzylidene  0   *Benzylidene Compounds *Pyrazolones. Indian J Exp Biol 1994 Aug;32(8):544-7
N(1)-isonicotinoyl-3-methyl-4-(4-hydroxybenzilidene)-2-pyrazolin-5-one  103847-83-2   *Isonicotinic Acids *Pyrazolones Copper. J Chem Technol Biotechnol 1993;57(1):43-7
1-n-butyl-5-(4-chlorophenyl)-3-pyrazolidinone  0   *Pyrazolones. Yao Hsueh Hsueh Pao 1992;27(9):711-6
famprofazone  22881-35-2   *Pyrazolones Methamphetamine/*analogs & derivatives. Xenobiotica 1992 Mar;22(3):377-84
1-(4-methoxy)phenyl-3-methyl-5-pyrazolone  60798-06-3   *Pyrazolones. Anal Biochem 1991 Dec;199(2):256-68
PK 144  0   *Pyrazolones. Lab Delo 1990;(6):9
revenast  85673-87-6   *Pyridines *Pyrazolones. J Chromatogr 1987;419:351
1-phenyl-2,3-dimethyl-4-naphthalanmorpholinomethylpyrazolin-5-one  61517-79-1   *Morpholines *Pyrazolones. Vet Med Nauki 1986;23(9):81
losoxantrone  88303-60-0   *Anthraquinones *Pyrazolones.
Pharma Action Antineoplastic Agents 		Biochem Biophys Res Commun 1986;140(3):797
pyrazolone  39455-90-8   *Pyrazolones.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Coloring Agents 		Internist (Berlin) 1983;24(5):276
5-aminomethylpyrazolin-5-one  33512-95-7   *Pyrazolones. J Theor Biol 1982;97(2):267
technetium Tc 99m-4-methylaminophenazone  0   *Organotechnetium Compounds *Pyrazolones Dipyrone/*analogs & derivatives. Gastroenterology 1982;83(1):279
1-phenyl-3-methyl-4-(5'-nitrofurfuryl)-pyrazol-5-one  71188-80-2 3H-Pyrazol-3-one, 2,4-dihydro-5-methyl-4-((5-nitro-2-furanyl)methyl)-2-phenyl  *Pyrazolones. Acta Pol Pharm 35(6):629;1978
1-nitrophenyl-3-methyl-4-(5'-nitrofurfuryl)pyrazol-5-one  0   *Pyrazolones. Acta Pol Pharm 35(6):629;1978
nafazatrom  59040-30-1 3H-Pyrazol-3-one, 2,4-dihydro-5-methyl-2-(2-(2-naphthalenyloxy)ethyl)  *Pyrazolones.
Pharma Action Antineoplastic Agents ; Fibrinolytic Agents ; Lipoxygenase Inhibitors 		Arzneim Forsch 29(1):54;1979; Lancet I(8115):518;1979
sudan yellow 3G  4314-14-1   *Azo Compounds *Pyrazolones Food Coloring Agents. Bratisl Lek Listy 66(4):416;1976
L.N. 1520  56693-29-9 2,4-dihydro-4-(hydroxymethylene)-5-phenyl-2-(3-(trifluoromethyl)phenyl)-3H-pyrazol-3-one, sodium salt  *Pyrazolones. Therapie 31:541;1976
picrolonic acid  550-74-3   *Pyrazolones. J Am Chem Soc 99(10):3491;1977; J Assoc Off Anal Chem 59(3):683;1976; Mutat Res 28(1):127;1975
4-amino-1-phenylpyrazolone  0   *Pyrazolones. Eur J Biochem 38(1):73;1973
4-bromo-3-(2-formamidophenyl)thiomethyl-2-methyl-1-phenyl-3-pyrazolin-5-one  0   *Pyrazolones. J Pharm Soc Jap 93(2):207;1973
caffeine, camylofin, ergotamine, mecloxamine, propyphenazone drug combination  0   *Caffeine *Ergotamine *Propylamines *Pyrazolones Drug Combinations Glycine/*analogs & derivatives. Lebanese Med J 25(4):316;1972
4-(4-tert-butylbenzoyl)-3-methyl-1-phenyl-2-pyrazolin-5-one  0   *Pyrazolones. Applied Microbiol 22(6):1174;1971

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy