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Phenethylamines
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Definition
: A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed)
Examples
Albuterol
;
Amphetamines
;
Butoxamine
;
Dexfenfluramine
;
Dimethoxyphenylethylamine
;
Dobutamine
;
Ephedrine
;
Fendiline
;
Fenfluramine
;
Hexoprenaline
;
2-Hydroxyphenethylamine
;
Isoxsuprine
;
Mescaline
;
Methoxamine
;
p-Methoxy-N-methylphenethylamine
;
Nylidrin
;
Octopamine
;
Oxyfedrine
;
Prenylamine
;
Pseudoephedrine
;
Ritodrine
;
Selegiline
;
Suloctidil
;
Verapamil
Other names
Phenylethylamines
Substance
CAS Registry & name
Categories
Source
Drugs
*
4-
ethyl-
2,5-
dimethoxyphenethylamine
0
*Phenethylamines
Street Drugs.
MMWR Morb Mortal Wkly Rep. 2012 Feb 10;61(5):85-8.
credneramide A
0
*Phenethylamines
*Fatty Acids
Neurotransmitter Agents.
J Nat Prod. 2012 Jan 27;75(1):60-6
2-
(4-
iodo-
2,5-
dimethoxyphenyl)-
N-
(2-
methoxybenzyl)ethanamine
0
*Benzylamines
*Phenethylamines
Carbon Radioisotopes
Ligands
Receptor, Serotonin, 5-HT2A.
J Nucl Med 2010 Nov;51(11):1763-70
N-
allylidene-
1,1-
diphenylethanamine
0
*Phenethylamines.
Org Lett. 2010 Aug 20;12(16):3571-3
N-
((6-
(methyloxy)-
4'-
(trifluoromethyl)-
3-
biphenylyl)methyl)-
1-
phenylethanamine
0
*Biphenyl Compounds
*Phenethylamines.
Eur J Pharmacol 2009 Aug 15;616(1-3):306-13
4'-
(2-
((2-
(3-
chlorophenyl)-
2-
hydroxyethyl)amino)ethyl)-
3-
methoxybiphenyl-
4-
carboxylic acid
0
*Biphenyl Compounds
*Phenethylamines
Receptors, Adrenergic, beta-3/agonists.
Br J Pharmacol 2009 Jan;156(1):127-34
N,N-
dimethyl-
3,4-
methylenedioxyphenethylamine
0
*Phenethylamines.
J Psychoactive Drugs 2008 Jun;40(2):219-22
BVT116429
0
*Phenethylamines
*Thiazoles.
BMC Pharmacol. 2008;8() (dup#1):3
2-
(2,5-
dimethoxy-
4-
isopropylsulfanylphenyl)ethanamine
0
*Phenethylamines
Psychoses, Substance-Induced
Designer Drugs.
Psychiatry Clin Neurosci 2008 Apr;62(2):243
phenoprolamine hydrochloride
0
*Phenethylamines.
Biomed Chromatogr 2008 Mar;22(3):333-8
hostasinine A
0
*Phenethylamines
Alkaloids.
Org Lett. 2007 Dec 6;9(25):5279-81
meta-
phenylene ethynylene
0
*Alkynes
*Phenethylamines.
Antimicrob Agents Chemother 2007 Nov;51(11):4125-32
2,5-
dimethoxy-
4-
methylthiophenethylamine
0
*Phenethylamines.
J Chromatogr A 2007 Aug 3;1159(1-2):198-202
2,5-
dimethoxy-
4-
cyclohexylthiophenethylamine
0
*Phenethylamines.
J Chromatogr A 2007 Aug 3;1159(1-2):198-202
2,5-
dimethoxy-
4-
methyl-
beta-
phenethylamine
0
*Phenethylamines.
J Mass Spectrom 2006 Nov;41(11):1509-19
N,N-
dimethyl-
1-
phenethylamine
0
*Phenethylamines.
Bioorg Med Chem. 2005 Apr 15;13(8):3047-55
2-
dimethylamino-
1-
(4-
hydroxyphenyl)-
8,10-
dimethyl-
6-
dodecene-
3-
one
0
*Ketones
*Phenethylamines.
J Antibiot (Tokyo) 2004 Sep;57(9):569-72
2,5-
dimethoxy-
4-
n-
propylthiophenethylamine
0
*Phenethylamines
Substance-Related Disorders.
J Anal Toxicol. 2003 Oct;27(7):493-8
1-
phenylethylaminopyridine
0
*Phenethylamines
*Pyridines.
J Org Chem 2003 May 30;68(11):4527-30
2-
(2-
methylphenoxy)-
1-
phenylethanamine
0
*Phenethylamines
*Phenyl Ethers.
J Med Chem 2003 Nov 20;46(24):5238-48
N-
acetyl-
N-
(2-
(naphth-
1-
yloxy)ethyl)-
4-
methanesulfonamidophenethylamine
0
*Phenethylamines
*Sulfonamides.
J Med Chem 2002 Jul 4;45(14):2953-69
GYKI 16638
0
*Phenethylamines
*Sulfonamides.
Eur J Pharmacol 2000 Sep 15;404(1-2):181-90
hermitamide A
0
*Amides
*Phenethylamines.
J Nat Prod 2000 Jul;63(7):952-5
2-
(N-
methyl-
N-
(4-
toluenesulfonyl)amino)-
1-
phenylpropan-
1-
ol
0
*Phenethylamines
*Sulfonamides.
Acta Crystallogr C 2000 Feb;56( Pt 2):227-8
KCB 328
0
*Phenethylamines
*Sulfonamides
Potassium Channels/antagonists & inhibitors.
J Cardiovasc Pharmacol 1998 Apr;31(4):609-17
desmethylmebeverine alcohol
155172-67-1
*Phenethylamines.
J Chromatogr B Biomed Appl 1996 Jul 12;602(2):273-81
aletamine
4255-23-6 alpha-
2-
propenyl benzeneethanamine
*Phenethylamines.
CT 435
0
*Phenethylamines.
J Cell Sci 1994 Nov;107(Pt 11):3055-64
1-
(2,5-
dimethoxy-
4-
(trifluoromethyl)phenyl)-
2-
aminopropane
0
*Phenethylamines.
J Med Chem 1994 Dec 9;37(25):4346-51
1,4-
dihydro-
-
2,6-
dimethyl-
4-
(2-
trifluoromethylphenyl)-
3,5-
pyridinedicarboxylic acid 2-
(4,4-
difluoro-
5,7-
dimethyl-
4-
bora-
3a,4a-
diaza-
3-
(s-
indacene)propionylamino)ethylethyl ester
0
*Dihydropyridines
*Phenethylamines.
Biochemistry 1994 Oct 4;33(39):11875-83
FPL 12495
118910-28-4
*Phenethylamines
Stereoisomerism.
Drug Metab Dispos 1994 May-Jun;22(3):443-6
4-
dimethylaminophenethylamine
52632-05-0
*Phenethylamines.
Life Sci 1994;54(25):1955-63
bamethan
3703-79-5 Benzenemethanol, alpha-
((butylamino)methyl)-
4-
hydroxy
*Ethanolamines
*Phenethylamines.
Pharma Action
Vasodilator Agents
2-
(N-
n-
3-
fluoropropyl-
N-
(4-
fluorophenyl)ethylamino)-
5-
hydroxytetralin
147703-11-5
*Phenethylamines
*Tetrahydronaphthalenes
Fluorine Radioisotopes.
Appl Radiat Isot 1993 Mar;44(3):473-80
2-
(N-
n-
3-
fluoropropyl-
N-
(4-
methylphenyl)ethylamino)-
5-
hydroxytetralin
147703-10-4
*Phenethylamines
*Tetrahydronaphthalenes
Fluorine Radioisotopes.
Appl Radiat Isot 1993 Mar;44(3):473-80
1,2,3-
tristriphenylethylaminopropane
144785-93-3
*Phenethylamines.
Ukr Biokhim Zh 1992 Sep-Oct;64(5):100-3
RG 14893
141835-49-6
*Naphthols
*Phenethylamines.
J Med Chem 1992 Oct 30;35(22):4253-5
PD 136450
139067-52-0
*Indoles
*Phenethylamines.
Gastroenterology 1992 Nov;103(2):1596-601
mebeverine alcohol
14367-47-6
*Phenethylamines.
Anal Chem 1992 Apr 1;64(7):802-6
14-
debromoprearaplysillin I
136685-30-8
*Hydroxylamines
*Phenethylamines.
J Nat Prod 1991 Jul-Aug;54(4):1137-40
14-
debromoaraplysillin I
136685-29-5 1-
Oxa-
2-
azaspiro(4.5)deca-
2,6,8-
triene-
3-
carboxamide, N-
(3-
(4-
(2-
aminoethyl)-
2-
bromophenoxy)propyl)-
7,9-
dibromo-
10-
hydroxy-
8-
methoxy-
, (5S-
trans)
*Isoxazoles
*Phenethylamines.
J Nat Prod 1991 Jul-Aug;54(4):1137-40
araplysillin I
129313-98-0 1-
Oxa-
2-
azaspiro(4.5)deca-
2,6,8-
triene-
3-
carboxamide, N-
(3-
(4-
(2-
aminoethyl)-
2,6-
dibromophenoxy)propyl)-
7,9-
dibromo-
10-
hydroxy-
8-
methoxy-
, (5S-
trans)
*Isoxazoles
*Phenethylamines.
J Nat Prod 1991 Jul-Aug;54(4):1137-40
5-
amino-
2,4-