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Indazoles

More information in Books or onNLM PubMed
Definition:      
Examples Benzydamine; Granisetron
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2'-(tert-butyl)-1-(1H-indazole-5-carbonyl)-2'H-spiro(piperidine-4,5'-pyrano(3,2-c)pyrazol)-7'(6'H)-one  0   *Indazoles *Spiro Compounds Acetyl-CoA Carboxylase. J Med Chem. 2012 Jan 26;55(2):935-42.
11-(2-methylpropyl)-12,13-dihydro-2-methyl-8-(pyrimidin-2-ylamino)-4H-indazolo(5,4-a)pyrrolo(3,4-c)carbazol-4-one  0   *Carbazoles *Indazoles. J Med Chem. 2012 Jan 26;55(2):903-13.
2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3yl)vinyl)-1H-pyrazol-1-yl)ethanol  0   *Indazoles Receptors, Fibroblast Growth Factor/antagonists & inhibitors. Mol Cancer Ther. 2011 Nov;10(11):2200-10.
PF 04929113  0   *Benzamides *Indazoles. Cancer Res 2011 Sep 1;71(17):5838-49
2-(4-acetyloxycyclohexylamino)-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)-benzamide  0   *Benzamides *Indazoles HSP90 Heat-Shock Proteins/antagonists & inhibitors. Bioorg Med Chem Lett 2011 Mar 15;21(6):1675-7
N-(2-(1H-indazol-3-yl)-1H-pyrrole(3,2-b)pyridin-5-yl)-4-chloro-N-methylbenzamide  0   *Benzamides *Indazoles. Mol Cell Biochem 2010 Dec;345(1-2):13-21
N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine  0   *Aminopyridines *Indazoles. J Biol Chem 2011 Jan 21;286(3):1737-47
GSK 2334470  0   *Indazoles *Pyrimidines. Biochem J 2010 Dec 22;433(2):357-69
N-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochloride  0   *Bicyclo Compounds *Indazoles. J Pharmacol Exp Ther. 2011 Jan;336(1):242-53
N-(3-(methylthio)-1-phenyl-1H-indazol-6-yl)piperidine-4-carboxamide  0   *Indazoles *Piperidines Fructokinases/antagonists & inhibitors. J Med Chem 2010 Nov 25;53(22):7979-91
3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole  0   *Indazoles *Sulfones Receptors, Serotonin. J Med Chem 2010 Nov 11;53(21):7639-46
2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo(g)indazole-7-carboxylic acid  0   *Indazoles. J Med Chem 2010 Aug 26;53(16):5979-6002
SGA 360  0   *Allyl Compounds *Indazoles Receptors, Aryl Hydrocarbon/antagonists & inhibitors. Chem Res Toxicol 2010 May 17;23(5):955-66
ABT 116  0   *Indazoles *Phenylurea Compounds TRPV Cation Channels. Bioorg Med Chem Lett 2010 Jun 1;20(11):3291-4
3-(1H-pyrrol-2-yl)-1H-indazole  0   *Indazoles *Pyrroles. Biol Trace Elem Res 2010 Jul;136(1):79-86
(1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo(f)indazol-5-yl)-(4-(trifluoromethyl)phenyl)methanol  0   *Indazoles. J Pharmacol Exp Ther 2010 Apr;333(1):281-9
PHA 408  0   *Indazoles *Isonicotinic Acids. J Pharm Sci 2010 Mar;99(3):1278-87
2-(2-chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole  0   *Indazoles. J Lipid Res 2009 Dec;50(12):2358-70
2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide  0   *Indazoles *Piperidines Poly(ADP-ribose) Polymerases/antagonists & inhibitors. J Med Chem 2009 Nov 26;52(22):7170-85
2-(1,1'-biphenyl)-4-yl-N-(5-(1,1-dioxo-1lambda(6)-isothiazolidin-2-yl)-1H-indazol-3-yl)acetamide  0   *Indazoles *Thiazolidines. Chemotherapy 2009;55(5):353-62
1-(9-phenylfluoren-9-yl)-imidazole  0   *Indazoles. J Pharm Biomed Anal. 2009 Nov 1;50(4):675-8
2-benzyl-3-(4-hydroxymethylphenyl)indazole  0   *Indazoles. Eur J Pharmacol 2009 Aug 1;615(1-3):207-17
KW 2449  0   *Indazoles *Piperazines. Blood 2009 Aug 20;114(8):1607-17
3,4-dihydropyrazino(1,2-b)indazole  0   *Indazoles *Pyrazines. J Comb Chem. 2009 May-Jun;11(3):341-4
3-(4-chlorophenyl)-2-(4-nitrophenylsulfonyl)-3,3a,4,5,6,7-hexahydro-2H-indazole  0   *Indazoles. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2960-4
PF 03376056  0   *Azetidines *Indazoles DNA Gyrase/antagonists & inhibitors. Drug Metab Lett 2009 Jan;3(1):28-34
(3S,3aR,6R,7E)-7-(4-methoxybenzylidene)-3,4,5,7-hexahydro-3-(4-methoxyphenyl)-2,6-dimethyl-2H-indazole  0   *Indazoles. Magn Reson Chem. 2009 Jun;47(6):488-96
1-((3,4,5-trimethoxyphenyl)carbonyl)-1H-indazol-5-amine  0   *Indazoles Ligands. J Med Chem 2009 Apr 23;52(8):2177-80
CEP 11988  0   *Carbazoles *Indazoles. Blood 2006 Feb 15;107(4):1617-23
carbene indazol-3-ylidene  0   *Indazoles. Phys Chem Chem Phys. 2009 Jan 14;11(2):341-8
2-(8,9-dihydro-7H-pyrano(2,3-g)indazol-1-yl)-1-methylethylamine  0   *Benzopyrans *Indazoles Receptors, Serotonin, 5-HT2/agonists. Pharmacol Biochem Behav 2009 Jan;91(3):307-14
3-(2-(4-(3-chloro-2-methylphenyl)-1-piperazinyl)ethyl)-5,6-dimethoxyindazole  0   *Indazoles *Piperazines Calmodulin/antagonists & inhibitors. Mol Pharmacol 2009 Jan;75(1):101-12
N-((5-(3-(4,6-difluoro-1H-benzimidazol-2-yl)-1H-indazol-5-yl)-4-methylpyridin-3-yl)methyl)ethanamine  0   *Benzimidazoles *Indazoles CDC2 Protein Kinase/antagonists & inhibitors Cyclin-Dependent Kinase 2/antagonists & inhibitors Cyclin-Dependent Kinase 4/antagonists & inhibitors. Cancer Chemother Pharamcol 2008 Nov;62(6):1091-101
3,4,5,6,7-pentabromo-1H-indazole  0   *Indazoles. Biochem J 2008 Nov 1;415(3):353-65
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine  0   *Indazoles *Sulfonamides Phosphatidylinositol 3-Kinases/antagonists & inhibitors. J Med Chem 2008 Sep 25;51(18):5522-32
1-(1-hexyl-6-(methyloxy)-1H-indazol-3-yl)-2-methyl-1-propanone  0   *Indazoles. J Pharmacol Exp Ther 2008 Oct;327(1):168-77
nigellidine-4-O-sulfite  0   *Indazoles *Sulfuric Acid Esters Alkaloids. J Nat Prod 2008 Jun;71(6):1111-2
4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide  0   *Indazoles *Quinazolinones Receptors, Calcitonin Gene-Related Peptide/antagonists & inhibitors. J Med Chem 2008 Aug 28;51(16):4858-61
1-((imidazolidin-2-yl)imino)-7-methylindazole  0   *Indazoles *Imidazolidines Receptors, Adrenergic, alpha-2/antagonists & inhibitors Imidazoline Receptors/antagonists & inhibitors. J Med Chem 2008 Jun 26;51(12):3599-608
1-((imidazolidin-2-yl)imino)indazole  0   *Indazoles *Imidazolidines Receptors, Adrenergic, alpha-2/antagonists & inhibitors Imidazoline Receptors/antagonists & inhibitors. J Med Chem 2008 Jun 26;51(12):3599-608
gamendazole  0   *Indazoles. Biol Reprod 2008 Jun;78(6):1127-38
5-nitroindazole  0   *Indazoles. Bioorg Med Chem 2008 May 1;16(9):5078-84
ABT 102  0   *Indazoles Urea/*analogs & derivatives. J Med Chem 2008 Feb 14;51(3):392-5
2-phenyl-1,2-dihydronaphtho(2,3-g)indazole-3,6,11-trione  0   *Anthraquinones *Indazoles. Cancer Res 2006 Oct 1;66(19):9722-30
N-(3-trichloromethyl-4-(8-azabicyclo(3.2.1)octan-8-yl)benzyl)-N'-(indazol-4-yl)urea  0   *Indazoles Urea/*analogs & derivatives TRPV Cation Channels/antagonists & inhibitors. J Med Chem 2007 Jul 26;50(15):3651-60
1-(2-aminopropyl)-1H-indazole-6-ol  0   *Indazoles Receptors, Serotonin, 5-HT2/agonists. J Ocul Pharmacol Ther 2007 Feb;23(1):1-13
piperazinyl indazole  0   *Indazoles *Piperazines. Chem Res Toxicol. 2006 Oct;19(10):1341-50
(1-benzo(1,3)dioxal-5-ylmethyl-piperidines-4-yl)-(5-chloro-1H-indazole-3-yl)-amine  0   *Indazoles *Piperidines. Eur J Pharmacol 2006 Jul 1;540(1-3):115-20
N-1H-indazol-4-yl-N'-(5-piperidin-1-yl-2,3-dihydro-1H-inden-1-yl)urea  0   *Indazoles Urea/*analogs & derivatives. J Neurosci 2006 Sep 13;26(37):9385-93
N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea  0   *Indazoles *Phenylurea Compounds Receptor Protein-Tyrosine Kinases/antagonists & inhibitors. Mol Cancer Ther 2006 Apr;5(4):995-1006
N-(7-indazolyl)benzenesulfonamide  0   *Indazoles *Sulfonamides. Bioorg Med Chem. 2006 Feb 15;14(4):1078-88
nigellicine  0   *Heterocyclic Compounds, 3-Ring *Indazoles. Org Lett 2005 Jun 9;7(12):2449-51
AG 013925  0   *Indazoles. Cancer Res 2005 Oct 15;65(20):9253-60
1-(2-aminopropyl)-1H-indazol-6-ol  0   *Indazoles Receptors, Serotonin, 5-HT2/agonists. J Med Chem 2006 Jan 12;49(1):318-28
3-(5-nitrofuryl)-7-(5-nitrofurfurylidene)-3,3a,4,5,6,7-hexahydro-2H-indazole  0   *Indazoles *Nitrofurans. Antibiot Khimioter. 2005;50(2-3):18-21
A 443654  0   *Indazoles *Indoles. Mol Cancer Ther 2005 Jun;4(6):977-86
axitinib  0   *Imidazoles *Indazoles. J Clin Oncol 2005 Aug 20;23(24):5473-83INLYTA
4,5-dihydro-1H-benzo(g)indazole  0   *Indazoles. Bioorg Med Chem. 2005 May 2;13(9):3309-20
1-(2-deoxy-beta-D-erythro-pentofuranosyl)-4-nitro-1H-indazole  0   *Indazoles Deoxyribonucleosides. Acta Crystallogr C. 2004 Jun;60(Pt 6):o387-9
indazolium trans-(tetrachlorobis(1H-indazole)ruthenate (III))  0   *Indazoles *Organometallic Compounds Ruthenium. J Pharmacol Exp Ther. 2005 Jan;312(1):281-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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